TargetMol

Tyrphostin A1

Product Code:
 
TAR-T7649
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T7649-5mg5mg£95.00
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Quantity:
TAR-T7649-1mL1 mL * 10 mM (in DMSO)£98.00
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TAR-T7649-10mg10mg£108.00
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Quantity:
TAR-T7649-25mg25mg£142.00
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Quantity:
TAR-T7649-50mg50mg£172.00
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Quantity:
TAR-T7649-100mg100mg£201.00
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Quantity:
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This product comes from: United States.
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Further Information

Bioactivity:
Tyrphostin A1 is an inhibitor of EGFR tyrosine kinase .
CAS:
2826-26-8
Formula:
C11H8N2O
Molecular Weight:
184.198
Pathway:
Tyrosine Kinase/Adaptors; Immunology/Inflammation; JAK/STAT signaling; Angiogenesis
Purity:
0.9913
SMILES:
COc1ccc(C=C(C#N)C#N)cc1
Target:
EGFR; Interleukin

References

Ogura T , Imanishi S , Shibamoto T . Activation of Background Membrane Conductance by the Tyrosine Kinase Inhibitor Tyrphostin A23 and Its Inactive Analog Tyrphostin A1 in Guinea Pig Ventricular Myocytes.[J]. The Japanese Journal of Pharmacology, 2001, 87(3):235-239. Du C , Bright J J , Sriram S . Inhibition of CD40 signaling pathway by tyrphostin A1 reduces secretion of IL-12 in macrophage, Th1 cell development and experimental allergic encephalomyelitis in SJL/J mice[J]. Journal of Neuroimmunology, 2001, 114(1-2):69-79.