TargetMol

Se-Methylselenocysteine

Product Code:
 
TAR-T7727
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T7727-5mg5mg£102.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T7727-10mg10mg£125.00
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TAR-T7727-25mg25mg£182.00
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Quantity:
TAR-T7727-50mg50mg£249.00
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Quantity:
TAR-T7727-100mg100mg£337.00
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Quantity:
TAR-T7727-200mg200mg£470.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
Se-Methylselenocysteine is a potent chemopreventive agent in many test systems and has been shown to inhibit tumor promotion and induce apoptosis.
CAS:
26046-90-2
Formula:
C4H9NO2Se
Molecular Weight:
182.092
Pathway:
Proteases/Proteasome; Apoptosis
Purity:
0.98
SMILES:
C[Se]C[C@H](N)C(O)=O
Target:
BCL; IAP; Caspase

References

Yang H, Jia X. Safety evaluation of Se-methylselenocysteine as nutritional selenium supplement: acute toxicity, genotoxicity and subchronic toxicity. Regul Toxicol Pharmacol. 2014 Dec;70(3):720-7. doi: 10.1016/j.yrtph.2014.10.014. PubMed PMID: 25444999. Avila FW, Yang Y, Faquin V, Ramos SJ, Guilherme LR, Thannhauser TW, Li L. Impact of selenium supply on Se-methylselenocysteine and glucosinolate accumulation in selenium-biofortified Brassica sprouts. Food Chem. 2014 Dec 15;165:578-86. doi: 10.1016/j.foodchem.2014.05.134. PubMed PMID: 25038715. Cao S, Durrani FA, T?th K, Rustum YM. Se-methylselenocysteine offers selective protection against toxicity and potentiates the antitumour activity of anticancer drugs in preclinical animal models. Br J Cancer. 2014 Apr 2;110(7):1733-43. doi: 10.1038/bjc.2014.85. PubMed PMID: 24619073; PubMed Central PMCID: PMC3974093. Yao Z, Zhang Y, Li H, Deng Z, Zhang X. Synergistic effect of Se-methylselenocysteine and vitamin E in ameliorating the acute ethanol-induced oxidative damage in rat. J Trace Elem Med Biol. 2015 Jan;29:182-7. doi: 10.1016/j.jtemb.2014.08.004. PubMed PMID: 25213679.