TargetMol

α-MSH

Product Code:
 
TAR-T7813
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T7813-1mg1mg£127.00
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TAR-T7813-5mg5mg£201.00
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TAR-T7813-10mg10mg£299.00
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TAR-T7813-25mg25mg£454.00
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TAR-T7813-50mg50mg£622.00
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Quantity:
TAR-T7813-100mg100mg£871.00
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This product comes from: United States.
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Further Information

Bioactivity:
α-MSH is amide stimulates melanocortin 1 receptor that results in the activation of adenylyl cyclase.
CAS:
581-05-5
Formula:
C77H109N21O19S
Molecular Weight:
1664.91
Pathway:
Neuroscience; GPCR/G Protein
Purity:
1
SMILES:
CSCC[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(C)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(N)=O
Target:
Melanocortin Receptor; Adenylyl cyclase

References

Zhang L, Wan M, Tohti R, et al.Requirement of Zebrafish Adcy3a and Adcy5 in Melanosome Dispersion and Melanocyte Stripe Formation.International Journal of Molecular Sciences.2022, 23(22): 14182. Jo H, et al. Synthesis and biological evaluation of caffeic acid derivatives as potent inhibitors of ?-MSH-stimulated melanogenesis. Bioorg Med Chem Lett. 2017 Aug 1;27(15):3374-3377. Lu X Y , Barsh G S , Akil H , et al. Interaction between ?-melanocyte-stimulating hormone and corticotropin-releasing hormone in the regulation of feeding and hypothalamo-pituitary-adrenal responses[J]. Journal of Neuroscience the Official Journal of the Society for Neuroscience, 2003, 23(21):7863. Jo H , Choi M , Sim J , et al. Synthesis and Biological Evaluation of Caffeic Acid Derivatives as Potent Inhibitors of ?-MSH-stimulated Melanogenesis[J]. Bioorganic & Medicinal Chemistry Letters, 2017:S0960894X17306133.