TargetMol

FIT-039

Product Code:
 
TAR-T8972
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T8972-5mg5mg£111.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
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TAR-T8972-1mL1 mL * 10 mM (in DMSO)£116.00
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TAR-T8972-10mg10mg£138.00
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TAR-T8972-25mg25mg£209.00
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TAR-T8972-50mg50mg£294.00
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TAR-T8972-100mg100mg£406.00
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Quantity:
TAR-T8972-500mg500mg£864.00
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This product comes from: United States.
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Further Information

Bioactivity:
FIT-039 is a selective and ATP-competitive, orally active inhibitor of CDK9( IC50 : 5.8 μM;CDK9/cyclin T1). FIT-039 inhibits replication of HSV-1 (IC50 of 0.69 μM), HSV-2, human adenovirus, and human CMV. FIT-039 is a promising antiviral agent for inhibiting drug-resistant HSVs and other DNA viruses.
CAS:
1113044-49-7
Formula:
C17H18FN3S
Molecular Weight:
315.41
Pathway:
Microbiology/Virology; DNA Damage/DNA Repair; Cell Cycle/Checkpoint;
Purity:
1
SMILES:
Fc1ccc(N2CCCCC2)c(NC(=S)c2ccncc2)c1
Target:
DNA/RNA Synthesis; CDK; HSV

References

Ajiro M , Sakai H , Onogi H , et al. CDK9 Inhibitor FIT-039 Suppresses Viral Oncogenes E6 and E7 and Has a Therapeutic Effect on HPV-Induced Neoplasia.[J]. 2018.