TargetMol

FLTX1

Product Code:
 
TAR-T8984
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T8984-1mg1mg£149.00
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TAR-T8984-5mg5mg£282.00
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TAR-T8984-1mL1 mL * 10 mM (in DMSO)£302.00
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TAR-T8984-10mg10mg£402.00
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TAR-T8984-25mg25mg£626.00
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TAR-T8984-50mg50mg£862.00
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TAR-T8984-100mg100mg£1,139.00
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TAR-T8984-500mg500mg£2,207.00
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This product comes from: United States.
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Further Information

Bioactivity:
FLTX1, a fluorescent Tamoxifen derivative that can specifically label intracellular Tamoxifen-binding sites (estrogen receptors) under permeabilized and non-permeabilized conditions. FLTX1 exhibits the potent antiestrogenic properties of Tamoxifen in breast cancer cells. FLTX1 is devoid of the estrogenic agonistic effect on the uterus.
CAS:
1481401-71-1
Formula:
C31H28N4O4
Molecular Weight:
520.589
Pathway:
Endocrinology/Hormones
Purity:
0.9846
SMILES:
CCC(=C(c1ccccc1)c1ccc(OCCN(C)c2ccc([N+]([O-])=O)c3nonc23)cc1)c1ccccc1
Target:
Estrogen Receptor/ERR; Estrogen/progestogen Receptor

References

Morales A, et, al. Colocalization of Estrogen Receptors with the Fluorescent Tamoxifen Derivative, FLTX1, Analyzed by Confocal Microscopy. Methods Mol Biol. 2016;1366:163-173. https://pubmed.ncbi.nlm.nih.gov/23727370/