TargetMol

CA-4948

Product Code:
 
TAR-T9027
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T9027-1mg1mg£95.00
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TAR-T9027-2mg2mg£106.00
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TAR-T9027-5mg5mg£127.00
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TAR-T9027-1mL1 mL * 10 mM (in DMSO)£132.00
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TAR-T9027-10mg10mg£142.00
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TAR-T9027-25mg25mg£213.00
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TAR-T9027-50mg50mg£334.00
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TAR-T9027-100mg100mg£523.00
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This product comes from: United States.
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Further Information

Bioactivity:
Emavusertib is a potent IRAK4/FLT3 inhibtor. CA-4948 with anti-tumor activity.
CAS:
1801344-14-8
Formula:
C24H25N7O5
Molecular Weight:
491.508
Pathway:
Tyrosine Kinase/Adaptors; Angiogenesis; NF-κb; Immunology/Inflammation
Purity:
0.9962
SMILES:
Cc1cc(ccn1)-c1nc(co1)C(=O)Nc1cc2oc(nc2nc1N1CC[C@@H](O)C1)N1CCOCC1
Target:
IRAK; FLT

References

Wiese MD, et al. Investigational IRAK-4 inhibitors for the treatment of rheumatoid arthritis. Expert Opin Investig Drugs. 2020 Apr 17:1-8. Bhumireddy A . Discovery of CA-4948, an Orally Bioavailable IRAK4 Inhibitor for Treatment of Hematologic Malignancies[J]. Chemistry Letters, 2020, 11(12).