TargetMol

Caroverine hydrochloride

Product Code:
 
TAR-T9133
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T9133-5mg5mg£102.00
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TAR-T9133-1mL1 mL * 10 mM (in DMSO)£105.00
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TAR-T9133-10mg10mg£122.00
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TAR-T9133-25mg25mg£177.00
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TAR-T9133-50mg50mg£254.00
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TAR-T9133-100mg100mg£389.00
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TAR-T9133-200mg200mg£538.00
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TAR-T9133-500mg500mg£804.00
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Further Information

Bioactivity:
Caroverine HCL is a potent, competitive and reversible antagonist of NMDA and AMPA glutamate receptor. It is also an antioxidant and calcium-blocking agent that exhibits vasorelaxant action, and can be used for the research of inner ear tinnitus.
CAS:
55750-05-5
Formula:
C22H28ClN3O2
Molecular Weight:
401.94
Pathway:
Neuroscience; Membrane transporter/Ion channel
Purity:
0.9837
SMILES:
Cl.CCN(CC)CCn1c2ccccc2nc(Cc2ccc(OC)cc2)c1=O
Target:
GluR; NMDAR; iGluR

References

Ishida Y, et, al. Vasorelaxant action of caroverine fumarate (a quinoxaline derivative), a calcium-blocking agent. Br J Pharmacol. 1980;71(1):343-8. Duan M, et, al. Low-dose, long-term caroverine administration attenuates impulse noise-induced hearing loss in the rat. Acta Otolaryngol. 2006 Dec;126(11):1140-7.