TargetMol

FR054

Product Code:
 
TAR-T9468
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T9468-5mg5mg£102.00
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Quantity:
TAR-T9468-1mL1 mL * 10 mM (in DMSO)£105.00
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Quantity:
TAR-T9468-10mg10mg£118.00
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Quantity:
TAR-T9468-25mg25mg£146.00
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Quantity:
TAR-T9468-50mg50mg£173.00
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Quantity:
TAR-T9468-100mg100mg£230.00
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Quantity:
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This product comes from: United States.
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Further Information

Bioactivity:
FR054 is an inhibitor of the Hexosamine Biosynthetic Pathway (HBP) enzyme PGM3, with a remarkable anti-breast cancer effect. FR054 induces in different breast cancer cells a dramatic decrease in cell proliferation and survival.
CAS:
35954-65-5
Formula:
C28H37N2O16
Molecular Weight:
657.6
Purity:
0.98
SMILES:
CC(OC[C@H]([C@H]1OC(C)=O)O[C@@H]2OC(C)=N[C@@H]2[C@H]1OC(C)=O)=OCC(OC[C@H]([C@H]1OC(C)=O)O[C@@H]2OC(C)=N[C@@H]2[C@H]1OC(C)=O)=O

References

Francesca Ricciardiello, et al.Inhibition of the Hexosamine Biosynthetic Pathway by targeting PGM3 causes breast cancer growth arrest and apoptosis.Cell Death Dis . 2018 Mar 7;9(3):377.