TargetMol

dencichine

Product Code:
 
TAR-TL0001
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-TL0001-1mg1mg£103.00
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TAR-TL0001-5mg5mg£143.00
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TAR-TL0001-10mg10mg£173.00
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TAR-TL0001-25mg25mg£243.00
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TAR-TL0001-50mg50mg£326.00
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This product comes from: United States.
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Further Information

Bioactivity:
Dencichine is a neurotoxic agent. Dencichine is a haemostatic agent, the hemostatic effect relates to modulation of the coagulation system, platelet aggregation and fibrinolytic system. It has renoprotective effect, it could significantly prevent the progression of diabetic nephropathy possibly attribute to down-regulation of the TGF-β/Smad pathway and rebalance the deposition and degradation of ECM proteins.
CAS:
5302-45-4
Formula:
C5H8N2O5
Molecular Weight:
176.128
Pathway:
; Chromatin/Epigenetic; Metabolism
Purity:
0.98
SMILES:
N[C@@H](CNC(=O)C(O)=O)C(O)=O
Target:
HIF/HIF Prolyl-Hydroxylase

References

Xie G X, et al. Analysis of dencichine in Panax notoginseng by gas chromatography?mass spectrometry with ethyl chloroformate derivatization[J]. Journal of Pharmaceutical & Biomedical Analysis, 2007, 43(3):920-925. Li J, et al. Dencichine ameliorates kidney injury in induced type II diabetic nephropathy via the TGF-?/Smad signalling pathway[J]. European Journal of Pharmacology, 2017, 812:196.