TargetMol

1,2,3,6-Tetragalloylglucose

Product Code:
 
TAR-TN1160
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-TN1160-1mg1mg£228.00
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TAR-TN1160-5mg5mg£470.00
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TAR-TN1160-10mg10mg£654.00
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TAR-TN1160-1mL1 mL * 10 mM (in DMSO)£871.00
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TAR-TN1160-25mg25mg£978.00
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TAR-TN1160-50mg50mg£1,291.00
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Further Information

Bioactivity:
1,2,3,6-Tetragalloylglucose has antioxidative activity, it also shows the most potent anticomplement activity (IC50 = 34 microM). 1,2,3,6-Tetragalloylglucose is also a potent inhibitor of UDP glucuronosyltransferase 1 A1 (UGT1A1, Ki = 1.68 μM).
CAS:
79886-50-3
Formula:
C34H28O22
Molecular Weight:
788.576
Pathway:
Metabolism
Purity:
0.9843
SMILES:
O[C@@H]1[C@@H](COC(=O)c2cc(O)c(O)c(O)c2)O[C@@H](OC(=O)c2cc(O)c(O)c(O)c2)[C@H](OC(=O)c2cc(O)c(O)c(O)c2)[C@H]1OC(=O)c1cc(O)c(O)c(O)c1
Target:
LDL; UGT

References

Ngoc TM, et al. Antioxidative activities of galloyl glucopyranosides from the stem-bark of Juglans mandshurica. Biosci Biotechnol Biochem. 2008 Aug;72(8):2158-63. Park JB, et al. Identification and characterization of in vitro inhibitors against UDP-glucuronosyltransferase 1A1 in uva-ursi extracts and evaluation of in vivo uva-ursi-drug interactions. Food Chem Toxicol. 2018 Oct;120:651-661.