TargetMol

Decursinol angelate

Product Code:
 
TAR-TN1557
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-TN1557-1mg1mg£95.00
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TAR-TN1557-5mg5mg£128.00
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TAR-TN1557-1mL1 mL * 10 mM (in DMSO)£145.00
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TAR-TN1557-10mg10mg£164.00
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TAR-TN1557-25mg25mg£270.00
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TAR-TN1557-50mg50mg£370.00
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Quantity:
TAR-TN1557-100mg100mg£514.00
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This product comes from: United States.
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Further Information

Bioactivity:
Decursinol angelate has anti-tumor, anti-inflammatory, anti-oxidant, and hepatoprotective activities, it inhibits VEGF-induced angiogenesis via suppression of the VEGFR-2-signaling pathway; it also suppresses invasion and inflammatory activation of cancer cells through modulation of PI3K/AKT, ERK and NF-kappaB, its anti-inflammatory activity may contribute to its anti-cancer activity.
CAS:
130848-06-5
Formula:
C19H20O5
Molecular Weight:
328.364
Pathway:
Tyrosine Kinase/Adaptors; MAPK; Cytoskeletal Signaling; Chromatin/Epigenetic; Angiogenesis
Purity:
0.9965
SMILES:
CC=C(C)C(=O)O[C@H]1Cc2cc3ccc(=O)oc3cc2OC1(C)C
Target:
ERK; VEGFR; PKC; JNK

References

Decursin and decursinol angelate improve wound healing by upregulating transcription of genes encoding extracellular matrix remodeling proteins, inflammatory cytokines, and growth factors in human keratinocytes.Biochem Biophys Res Commun. 2018 May 23;499(4):979-984.