TargetMol

Sanggenol L

Product Code:
 
TAR-TN2177
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-TN2177-5mg5mg£336.00
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Quantity:
TAR-TN2177-1mL1 mL * 10 mM (in DMSO)£352.00
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Further Information

Bioactivity:
Sanggenol L shows higher cytotoxicity against human oral tumor cell lines (HSC-2 and HSG) than against normal human gingival fibroblasts (HGF), it induces apoptosis via caspase activation and inhibition of NF-κB/IκBα? phosphorylation as a potent chemotherapeutic agent for ovarian cancers.
CAS:
329319-20-2
Formula:
C25H26O6
Molecular Weight:
422.477
Pathway:
NF-κb; Cell Cycle/Checkpoint
Purity:
0.98
SMILES:
CC(C)=CCCC1(C)Oc2cc(O)c3C(=O)CC(Oc3c2C=C1)c1ccc(O)cc1O
Target:
c-Myc; NF-κB

References

Isoprenylated flavonoids from the root bark of Morus alba and their hepatoprotective and neuroprotective activities.Arch Pharm Res. 2015 Nov;38(11):2066-75.