TargetMol

4-methyl-6-phenyl-2H-pyranone

Product Code:
 
TAR-TN2436
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-TN2436-25mg25mgEnquire
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TAR-TN2436-50mg50mgEnquire
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TAR-TN2436-5mg5mg£111.00
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TAR-TN2436-1mL1 mL * 10 mM (in DMSO)£112.00
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TAR-TN2436-10mg10mg£127.00
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Further Information

Bioactivity:
4-methyl-6-phenyl-2H-pyranone is derived from Scutellaria baicalensis Georgi and improves mitochondrial functionality to protect astrocytes against hydrogen peroxide-induced toxicity.
CAS:
4467-30-5
Formula:
C12H10O2
Molecular Weight:
186.21
Pathway:
Metabolism
Purity:
1
SMILES:
Cc1cc(oc(=O)c1)-c1ccccc1
Target:
Mitochondrial Metabolism

References

Singh S, et al. Discovery of a novel series of N-hydroxypyridone derivatives protecting astrocytes against hydrogen peroxide-induced toxicity via improved mitochondrial functionality. Bioorg Med Chem. 2017;25(4):1394-1405. Zhang Z , Ju T , Ye J H , et al. CO2 = CO + O: Redox-Neutral Lactamization and Lactonization of C?H Bonds with CO2[J]. Synlett, 2017, 28(07):741-750.