TargetMol

α-Conotoxin AuIB

Product Code:
 
TAR-TP2061
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-TP2061-5mg5mg£945.00
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Further Information

Bioactivity:
Selective antagonist of α3β4 nicotinic acetylcholine receptors. Displays > 100-fold selectivity over other receptor subunit combinations including α2β2, α2β4, α3β2, α4β2, α4β4 and α1β1γδ.
CAS:
216299-21-7
Formula:
C65H89N17O21S4
Molecular Weight:
1572.76
Purity:
0.98
SMILES:
0

References

Luo et al (1998) α-Conotoxin AuIB selectively blocks α3β4 nicotinic acetylcholine receptors and nicotine-evoked NE release. J.Neurosci. 18 8571 PMID: Park et al (2006) An α3β4 subunit combination acts as a major functional nicotinic acetylcholine receptor in male rat pelvic ganglion neurons. Pflugers Arch. 452 775 PMID: Nai et al (2003) Relating neuronal nicotinic acetylcholine receptor subtypes defined by subunit composition and channel function. Mol.Pharmacol. 63 311 PMID: