TargetMol

LSKL, Inhibitor of Thrombospondin (TSP-1) (TFA)

Product Code:
 
TAR-TP2147
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
 

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CodeSizePrice
TAR-TP2147-100mg100mgEnquire
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TAR-TP2147-50mg50mgEnquire
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TAR-TP2147-5mg5mg£136.00
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TAR-TP2147-10mg10mg£164.00
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TAR-TP2147-25mg25mg£257.00
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Further Information

Bioactivity:
LSKL, Inhibitor of Thrombospondin (TSP-1) TFA, a latency-associated protein (LAP)-TGFβ derived tetrapeptide, is a competitive antagonist of TGF-β1.
CAS:
TP2147
Formula:
C23H43F3N6O7
Molecular Weight:
572.62
Purity:
0.98
SMILES:
0

References

Laurent MA, et al. In silico characterization of the interaction between LSKL peptide, a LAP-TGF-beta derived peptide, and ADAMTS1. Comput Biol Chem. 2016 Apr;61:155-61. Liao F, et al. LSKL peptide alleviates subarachnoid fibrosis and hydrocephalus by inhibiting TSP1-mediated TGF-?1 signaling activity following subarachnoid hemorrhage in rats. Exp Ther Med. 2016 Oct;12(4):2537-2543. Epub 2016 Aug 31. Kuroki H, et al. Effect of LSKL peptide on thrombospondin 1-mediated transforming growth factor ? signal activation and liver regeneration after hepatectomy in an experimental model. Br J Surg. 2015 Jun;102(7):813-25.