TargetMol

AZ3451

Product Code:
 
TAR-TQ0012
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-TQ0012-2mg2mg£101.00
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TAR-TQ0012-5mg5mg£119.00
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TAR-TQ0012-1mL1 mL * 10 mM (in DMSO)£133.00
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TAR-TQ0012-10mg10mg£149.00
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TAR-TQ0012-25mg25mg£266.00
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TAR-TQ0012-50mg50mg£414.00
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Quantity:
TAR-TQ0012-100mg100mg£581.00
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This product comes from: United States.
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Further Information

Bioactivity:
AZ3451 is an allosteric antagonist of protease-activated receptor-2 (PAR2, IC50: 23 nM).
CAS:
2100284-59-9
Formula:
C30H27BrN4O3
Molecular Weight:
571.475
Pathway:
GPCR/G Protein
Purity:
0.9844
SMILES:
C[C@@H](C1CCCCC1)n1c(nc2cc(ccc12)C(=O)Nc1ccc(cc1)C#N)-c1cc2OCOc2cc1Br
Target:
Protease-activated Receptor

References

Cheng RKY, et al. Structural insight into allosteric modulation of protease-activated receptor 2. Nature. 2017 May 4;545(7652):112-115.