TargetMol

Corynoxine B

Product Code:
 
TAR-TQ0258
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-TQ0258-5mg5mg£257.00
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TAR-TQ0258-10mg10mg£377.00
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Further Information

Bioactivity:
Corynoxine B is a Beclin-1-dependent autophagy inducer. It is an natural alkaloid isolated from Uncaria rhynchophylla (Miq.) Jacks (Gouteng in Chinese).
CAS:
17391-18-3
Formula:
C22H28N2O4
Molecular Weight:
384.476
Pathway:
Autophagy
Purity:
0.98
SMILES:
CC[C@@H]1CN2CC[C@@]3([C@@H]2C[C@@H]1C(=C/OC)C(=O)OC)C(=O)Nc1ccccc31
Target:
Autophagy

References

Song JX, et al. HMGB1 is involved in autophagy inhibition caused by SNCA/?-synuclein overexpression: a process modulated by the natural autophagy inducer corynoxine B. Autophagy. 2014 Jan;10(1):144-54. Sakakibara I, et al. Effect of oxindole alkaloids from the hooks of Uncaria macrophylla on thiopental-induced hypnosis. Phytomedicine. 1998 Apr;5(2):83-6.