TargetMol

4-O-Methyl honokiol

Product Code:
 
TAR-T10153
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T10153-1mL1 mL * 10 mM (in DMSO)£181.00
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Quantity:
TAR-T10153-10mg10mg£229.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
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Further Information

Bioactivity:
4-O-Methyl honokiol, a natural neolignan isolated from Magnolia officinalis, acts as a PPARγ agonist and inhibits NF-κB activity, used for cancer and inflammation research.
CAS:
68592-15-4
Formula:
C19H20O2
Molecular Weight:
280.367
Purity:
0.98
SMILES:
COc1ccc(cc1CC=C)-c1cc(CC=C)ccc1O

References

1. Lee NJ, et al. 4-O-methylhonokiol, a PPAR? agonist, inhibits prostate tumour growth: p21-mediated suppression of NF-?B activity. Br J Pharmacol. 2013 Mar;168(5):1133-45. 2. Lee YJ, et al. Inhibitory effect of 4-O-methylhonokiol on lipopolysaccharide-induced neuroinflammation, amyloidogenesis and memory impairment via inhibition of nuclear factor-kappaB in vitro and in vivo models. J Neuroinflammation. 2012 Feb 19;9:35.