TargetMol

CDK9-IN-7

Product Code:
 
TAR-T10745
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T10745-1mg1mg£229.00
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TAR-T10745-5mg5mg£490.00
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TAR-T10745-1mL1 mL * 10 mM (in DMSO)£531.00
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TAR-T10745-10mg10mg£680.00
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TAR-T10745-25mg25mg£1,010.00
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TAR-T10745-50mg50mg£1,340.00
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Quantity:
TAR-T10745-100mg100mg£1,781.00
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Quantity:
TAR-T10745-500mg500mg£3,500.00
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This product comes from: United States.
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Further Information

Bioactivity:
CDK9-IN-7 is a highly selective and orally active CDK9/cyclin T inhibitor (IC50: 11 nM), which exhibits more potent over other CDKs (CDK4/cyclinD: 148 nM; CDK6/cyclinD: 145 nM).
CAS:
2369981-71-3
Formula:
C29H37N7O2S
Molecular Weight:
547.72
Pathway:
Cell Cycle/Checkpoint
Purity:
0.98
SMILES:
CN(C)C(=O)c1cc2cnc(Nc3ccc(NC(=O)CCCCCCCN=C=S)cc3)nc2n1C1CCCC1
Target:
CDK

References

Wang X, et al. Novel cyclin-dependent kinase 9 (CDK9) inhibitor with suppression of cancer stemness activity against non-small-cell lung cancer. Eur J Med Chem. 2019 Jul 25;181:111535.