TargetMol

Cytochalasin A

Product Code:
 
TAR-T10928
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T10928-10mg10mg£630.00
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Further Information

Bioactivity:
Cytochalasin A is a cell-permeable fungal toxin and is an oxidized derivative of cytochalasin B. Cytochalasin A is an inhibitor of HIV-1 protease (IC50 = 3 μM), inhibits actin polymerization and interferes with microtubule assembly by reacting with sulfhydryl groups. Antibiotic and bactericidal active agent.
CAS:
14110-64-6
Formula:
C29H35NO5
Molecular Weight:
477.601
Pathway:
Proteases/Proteasome; Microbiology/Virology
Purity:
0.98
SMILES:
[H][C@]12[C@H](Cc3ccccc3)NC(=O)[C@]11OC(=O)C=CC(=O)CCC[C@@H](C)CC=C[C@@]1([H])[C@H](O)C(=C)[C@H]2C
Target:
HIV Protease

References

1. Kerman K, et al. An electrochemical approach for the detection of HIV-1 protease. Chem Commun (Camb). 2007 Oct 7;(37):3829-31. 2. Antonio Bottalico, et al. Cytochalasins: Structure-activity relationships. Phytochemistry Volume 29, Issue 1, 1990.