TargetMol

JAK-IN-3

Product Code:
 
TAR-T11704
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T11704-5mg5mg£438.00
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TAR-T11704-50mg50mg£1,982.00
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Quantity:
TAR-T11704-100mg100mg£2,560.00
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This product comes from: United States.
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Further Information

Bioactivity:
JAK-IN-3 is a potent JAK inhibitor, with IC50 values of 3 nM, 5 nM, 34 nM and 70 nM for JAK3, JAK1, TYK2 and JAK2, respectively.
CAS:
1400876-94-9
Formula:
C18H20N4O3
Molecular Weight:
340.383
Pathway:
Microbiology/Virology; Immunology/Inflammation
Purity:
0.98
SMILES:
C[C@@H](O)[C@@H](CO)Nc1c(cnn2cc(cc12)-c1ccccc1)C(N)=O
Target:
CCR

References

1. Spergel SH, et al. Discovery of a JAK1/3 Inhibitor and Use of a Prodrug To Demonstrate Efficacy in a Model of Rheumatoid Arthritis. ACS Med Chem Lett. 2019 Feb 13;10(3):306-311.