TargetMol

MDM2-IN-1

Product Code:
 
TAR-T11982
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T11982-5mg5mg£270.00
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Quantity:
TAR-T11982-50mg50mg£1,026.00
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Quantity:
TAR-T11982-100mg100mg£1,564.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
MDM2-IN-1 is a synthetic MDM2-p53 interaction (MDM2) inhibitor and contains the trans (D-)configuration.
CAS:
1410737-09-5
Formula:
C23H21Cl2FN2O3
Molecular Weight:
463.33
Purity:
0.98
SMILES:
OC(=O)[C@@H]1NC2(CCCCC2)[C@]2([C@H]1c1cccc(Cl)c1F)C(=O)Nc1cc(Cl)ccc21

References

1. Aguilar A, et al. Design of chemically stable, potent, and efficacious MDM2 inhibitors that exploit the retro-mannich ring-opening-cyclization reaction mechanism in spiro-oxindoles. J Med Chem. 2014 Dec 26;57(24):10486-98.