TargetMol

ML334

Product Code:
 
TAR-T12078
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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TAR-T12078-100mg100mgEnquire
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TAR-T12078-50mg50mgEnquire
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This product comes from: United States.
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Further Information

Bioactivity:
ML334 is a potent, cell permeable NRF2 activator.
CAS:
1432500-66-7
Formula:
C26H26N2O5
Molecular Weight:
446.503
Purity:
0.98
SMILES:
OC(=O)[C@H]1CCCC[C@H]1C(=O)N1CCc2ccccc2[C@H]1CN1C(=O)c2ccccc2C1=O

References

1. Wen X, et al. Activation of NRF2 Signaling in HEK293 Cells by a First-in-Class Direct KEAP1-NRF2 Inhibitor. J Biochem Mol Toxicol. 2015 Jun;29(6):261-6. 2. Hu L, et al. Discovery of a small-molecule inhibitor and cellular probe of Keap1-Nrf2 protein-protein interaction. Bioorg Med Chem Lett. 2013 May 15;23(10):3039-43.