TargetMol

Naloxone benzoylhydrazone

Product Code:
 
TAR-T12168
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T12168-5mg5mg£1,171.00
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TAR-T12168-50mg50mg£2,303.00
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Quantity:
TAR-T12168-100mg100mg£3,042.00
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Further Information

Bioactivity:
Naloxone benzoylhydrazone is a prototypic κ3-opioid receptor agonist, and a partial agonist at the cloned μ and δ opioid receptors, and an antagonist at opioid-like NOP receptors, has potently analgesia effect.
CAS:
119630-94-3
Formula:
C26H27N3O4
Molecular Weight:
445.519
Pathway:
Neuroscience; GPCR/G Protein; Endocrinology/Hormones
Purity:
0.98
SMILES:
[H][C@@]12Oc3c4c(C[C@@]5([H])N(CC=C)CC[C@@]14[C@@]5(O)CCC2=N/NC(=O)c1ccccc1)ccc3O
Target:
Opioid Receptor

References

1. Olianas MC, et al. Agonist activity of naloxone benzoylhydrazone at recombinant and native opioid receptors. Br J Pharmacol. 2006 Feb;147(4):360-70. 2. Connor M, et al. Has the sun set on kappa3-opioid receptors? Br J Pharmacol. 2006 Feb;147(4):349-50. 3. Paul D, et al. Naloxone benzoylhydrazone (NalBzoH) analgesia. J Pharmacol Exp Ther. 1990 Nov;255(2):769-74. 4. Gistrak MA, et al. Pharmacological actions of a novel mixed opiate agonist/antagonist: naloxone benzoylhydrazone. J Pharmacol Exp Ther. 1989 Nov;251(2):469-76.