TargetMol

Oxotremorine M iodide

Product Code:
 
TAR-T12339
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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TAR-T12339-25mg25mgEnquire
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TAR-T12339-50mg50mgEnquire
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TAR-T12339-10mg10mg£105.00
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TAR-T12339-1mL1 mL * 10 mM (in DMSO)£109.00
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Further Information

Bioactivity:
Oxotremorine M iodide is an agonist of mAChR and potentiates NMDA receptors.
CAS:
3854-04-4
Formula:
C11H19IN2O
Molecular Weight:
322.19
Pathway:
Neuroscience
Purity:
0.9875
SMILES:
[I-].O=C1N(CC#CC[N+](C)(C)C)CCC1
Target:
AChR

References

1. Tran JA, et al. Differential coupling of muscarinic M1, M2, and M3 receptors to phosphoinositide hydrolysis in urinary bladder and longitudinal muscle of the ileum of the mouse. J Pharmacol Exp Ther. 2006 Aug;318(2):649-56. Epub 2006 May 4. 2. Zwart R, et al. A novel muscarinic receptor-independent mechanism of KCNQ2/3 potassium channel blockadeby Oxotremorine-M. Eur J Pharmacol. 2016 Nov 15;791:221-228. 3. Zwart R, et al. Oxotremorine-M potentiates NMDA receptors by muscarinic receptor dependent and independentmechanisms. Biochem Biophys Res Commun. 2018 Jan 1;495(1):481-486. 4. Ichikawa J, et al. Cholinergic modulation of basal and amphetamine-induced dopamine release in rat medial prefrontal cortex and nucleus accumbens. Brain Res. 2002 Dec 20;958(1):176-84.