TargetMol

Plecanatide acetate

Product Code:
 
TAR-T12501
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T12501-10mg10mg£630.00
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Further Information

Bioactivity:
Plecanatide acetate is a agonist of guanylate cyclase-C (GC-C) receptor( EC50 of 190 nM in T84 cells), and shows anti-inflammatory activity in models of murine colitis.
CAS:
1075732-84-1
Formula:
C67H108N18O28S4
Molecular Weight:
1741.94
Purity:
0.98
SMILES:
OC(C)=O.[NDECELCVNV ACTGCL]

References

1. Shailubhai K, et al. Plecanatide and dolcanatide, novel guanylate cyclase-C agonists, ameliorate gastrointestinal inflammation in experimental models of murine colitis. World J Gastrointest Pharmacol Ther. 2015 Nov 6;6(4):213-22.