TargetMol

TSHR antagonist S37a

Product Code:
 
TAR-T13217
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T13217-10mg10mg£604.00
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TAR-T13217-25mg25mg£1,099.00
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TAR-T13217-50mg50mg£1,669.00
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TAR-T13217-100mg100mg£2,464.00
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This product comes from: United States.
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Further Information

Bioactivity:
TSHR antagonist S37a is a selective antagonist of thyrotropin receptor (TSHR), with potential for the treatment of Graves' orbitopathy.
CAS:
2143452-20-2
Formula:
C25H20N2O3S2
Molecular Weight:
460.57
Purity:
0.98
SMILES:
[H][C@@]12C[C@@]([H])([C@@]3([H])[C@@H](c4sc(=O)[nH]c4S[C@@]13[H])c1ccccc1)[C@@]1([H])C(=O)N(C(=O)[C@@]21[H])c1ccccc1

References

1. Marcinkowski P, et al. A New Highly Thyrotropin Receptor-Selective Small-Molecule Antagonist with Potential for the Treatment of Graves' Orbitopathy. Thyroid. 2019 Jan;29(1):111-123.