TargetMol

Zoniporide hydrochloride hydrate

Product Code:
 
TAR-T13413
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T13413-5mg5mg£390.00
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Quantity:
TAR-T13413-50mg50mg£1,484.00
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Quantity:
TAR-T13413-100mg100mg£2,079.00
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This product comes from: United States.
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Further Information

Bioactivity:
Zoniporide hydrochloride hydrate is a potent and selective sodium-hydrogen exchanger type 1 (NHE-1) inhibitor. Zoniporide hydrochloride hydrate inhibits human NHE-1 with IC50 of 14 nM.
CAS:
863406-85-3
Formula:
C17H19ClN6O2
Molecular Weight:
374.83
Purity:
0.98
SMILES:
O.Cl.NC(=N)NC(=O)c1cnn(c1C1CC1)-c1cccc2ncccc12

References

1. Tracey WR, et al. Zoniporide: a potent and selective inhibitor of the human sodium-hydrogen exchanger isoform 1 (NHE-1). Cardiovasc Drug Rev. 2003 Spring;21(1):17-32. 2. Guzman-Perez A, et al. Discovery of zoniporide: a potent and selective sodium-hydrogen exchanger type 1 (NHE-1) inhibitor with high aqueous solubility. Bioorg Med Chem Lett. 2001 Mar 26;11(6):803-7.