TargetMol

N-Acetyl-5-hydroxytryptamine

Product Code:
 
TAR-T1354
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T1354-10mg10mg£96.00
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TAR-T1354-25mg25mg£109.00
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TAR-T1354-50mg50mg£124.00
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Further Information

Bioactivity:
N-Acetylserotonin (NAS), also known as Normelatonin, is the immediate precursor of melatonin. It is produced from serotonin by the enzyme aralkylamine N-acetyltransferase and is converted to melatonin by acetylserotonin O-methyltransferase. It can potently activate TrkB receptor.
CAS:
1210-83-9
Formula:
C12H14N2O2
Molecular Weight:
218.256
Pathway:
Metabolism; Tyrosine Kinase/Adaptors
Purity:
0.9991
SMILES:
CC(=O)NCCc1c[nH]c2ccc(O)cc12
Target:
Trk receptor; Endogenous Metabolite

References

1. Jang SW, et al. N-acetylserotonin activates TrkB receptor in a circadian rhythm. Proc Natl Acad Sci U S A. 2010 Feb 23;107(8):3876-81. 2. Chattoraj A, et al. Melatonin formation in mammals: in vivo perspectives. Rev Endocr Metab Disord. 2009 Dec;10(4):237-43.