TargetMol

HIF-2 α-IN-1

Product Code:
 
TAR-T15482
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T15482-5mg5mg£850.00
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Quantity:
TAR-T15482-50mg50mg£1,830.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T15482-100mg100mg£2,560.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
HIF-2α-IN-1 is an inhibitor of HIF-2α. In HIF-2α scintillation proximity assay, It also has an IC50 of less than 500 nM.
CAS:
1799948-06-3
Formula:
C16H8F5NO4S
Molecular Weight:
405.3
Purity:
0.98
SMILES:
O[C@@H]1c2c(ccc(Oc3cc(F)cc(c3)C#N)c2C(F)F)S(=O)(=O)C1(F)F

References

1. Bruick Richard Keith, et al. HIF-2? inhibitors for treating iron overload disorders. From PCT Int. Appl. (2016), WO 2016057242 A1 20160414. 2. Dixon Darryl David, et al. Preparation of cyclic sulfone and sulfoximine analogs as HIF-2? inhibitors. From PCT Int. Appl. (2015), WO 2015095048 A1 20150625.