TargetMol

L-902688

Product Code:
 
TAR-T15690
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T15690-5mg5mg£1,010.00
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TAR-T15690-50mg50mg£1,982.00
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Quantity:
TAR-T15690-100mg100mg£2,560.00
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This product comes from: United States.
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Further Information

Bioactivity:
L-902688 is an orally active EP4 receptor agonist (Ki: 0.38 nM; EC50: 0.6 nM). L-902688 displays >4,000-fold selective for EP4 over other EP and prostanoid receptors.
CAS:
634193-54-7
Formula:
C21H27F2N5O2
Molecular Weight:
419.477
Pathway:
GPCR/G Protein; Immunology/Inflammation
Purity:
0.98
SMILES:
[H][C@@](O)(C=C[C@H]1CCC(=O)N1CCCCCCc1nnn[nH]1)C(F)(F)c1ccccc1
Target:
Prostaglandin Receptor

References

1. Lai YJ, et al. EP4 Agonist L-902,688 Suppresses EndMT and Attenuates Right Ventricular Cardiac Fibrosis in Experimental Pulmonary Arterial Hypertension. Int J Mol Sci. 2018 Mar 3;19(3). pii: E727. 2. Young, R.N., Billot, X., Han, Y., et al. Discovery and synthesis of a potent, selective and orally bioavailable EP4 receptor agonist. Heterocycles. 2004, 64, 437-445.