TargetMol

Neurodazine

Product Code:
 
TAR-T16287
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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Further Information

Bioactivity:
Neurodazine is an imidazole-based small molecule, serves as a promoter of neurogenesisin pluripotent cells. Neurodazine selectively inhibits astrocyte differentiation of P19 cells. Neurodazine promotes neurogenesis by activating Wnt and Shh signaling pathways.
CAS:
937807-66-4
Formula:
C27H21ClN2O3
Molecular Weight:
456.93
Pathway:
Chromatin/Epigenetic
Purity:
0.98
SMILES:
COc1ccc(cc1)-c1nc([nH]c1-c1ccc(OC)cc1)-c1ccc(o1)-c1cccc(Cl)c1
Target:
DNA Methyltransferase

References

1. Kim GH, et al. Imidazole-based small molecules that promote neurogenesis in pluripotent cells. Angew Chem Int Ed Engl. 2014 Aug 25;53(35):9271-4. 2. Halder D, et al. Synthetic small molecules that induce neuronal differentiation in neuroblastoma and fibroblast cells. Mol Biosyst. 2015 Oct;11(10):2727-37.