TargetMol

Pimonidazole

Product Code:
 
TAR-T16537
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T16537-10mg10mg£102.00
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TAR-T16537-25mg25mg£135.00
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TAR-T16537-50mg50mg£193.00
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TAR-T16537-100mg100mg£303.00
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TAR-T16537-200mg200mg£388.00
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Further Information

Bioactivity:
Pimonidazole accumulates in hypoxic cells via covalent binding with macromolecules or by forming reductive metabolites after the reduction of its nitro group. It can be used for qualitative and quantitative assessment of tumor hypoxia. Pimonidazole is a novel hypoxia marker for the complementary study of tumor hypoxia and cell proliferation in tumors.
CAS:
70132-50-2
Formula:
C11H18N4O3
Molecular Weight:
254.29
Purity:
0.9957
SMILES:
OC(CN1CCCCC1)Cn1ccnc1[N+]([O-])=O

References

1. Varia MA, et al. Pimonidazole: a novel hypoxia marker for complementary study of tumor hypoxia and cell proliferation in cervical carcinoma. Gynecol Oncol. 1998 Nov;71(2):270-7. 2. Masaki Y, et al. Imaging Mass Spectrometry Revealed the Accumulation Characteristics of the 2-Nitroimidazole-Based Agent "Pimonidazole" in Hypoxia. PLoS One. 2016 Aug 31;11(8):e0161639.