TargetMol

Elocalcitol

Product Code:
 
TAR-T19869
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T19869-5mg5mg£2,456.00
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TAR-T19869-50mg50mg£4,874.00
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Quantity:
TAR-T19869-100mg100mg£6,898.00
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This product comes from: United States.
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Further Information

Bioactivity:
Elocalcitol is a calcitriol analog for inhibition of prostate cell growth.
CAS:
199798-84-0
Formula:
C29H43FO2
Molecular Weight:
442.659
Purity:
0.98
SMILES:
[H][C@@]12CC=C([C@@H](C)CC=CC(O)(CC)CC)[C@@]1(C)CCCC2=C/C=C1/C[C@@H](O)C[C@H](F)C1=C

References

1. Yang WS, Yu H, Kim JJ, Lee MJ, Park SK. Vitamin D-induced ectodomain shedding of TNF receptor 1 as a nongenomic action: D3 vs D2 derivatives. J Steroid Biochem Mol Biol. 2016 Jan;155(Pt A):18-25. doi: 10.1016/j.jsbmb.2015.09.019. Epub 2015 Sep 15. PubMed PMID: 26385608. 2. Streng T, Andersson KE, Hedlund P, Gratzke C, Baroni E, D'Ambrosio D, Benigni F. Effects on bladder function of combining elocalcitol and tolterodine in rats with outflow obstruction. BJU Int. 2012 Jul;110(2 Pt 2):E125-31. doi: 10.1111/j.1464-410X.2011.10838.x. Epub 2012 Jan 30. PubMed PMID: 22288904. 3. Mariani M, Vigan? P, Gentilini D, Camisa B, Caporizzo E, Di Lucia P, Monno A, Candiani M, Somigliana E, Panina-Bordignon P. The selective vitamin D receptor agonist, elocalcitol, reduces endometriosis development in a mouse model by inhibiting peritoneal inflammation. Hum Reprod. 2012 Jul;27(7):2010-9. doi: 10.1093/humrep/des150. Epub 2012 May 15. PubMed PMID: 22588001. 4. Sayegh L, Fuleihan Gel-H, Nassar AH. Vitamin D in endometriosis: a causative or confounding factor? Metabolism. 2014 Jan;63(1):32-41. doi: 10.1016/j.metabol.2013.09.012. Epub 2013 Oct 14. Review. PubMed PMID: 24135500.