TargetMol

Atorvastatin

Product Code:
 
TAR-T20765
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T20765-10mg10mg£107.00
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TAR-T20765-50mg50mg£121.00
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TAR-T20765-100mg100mg£148.00
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This product comes from: United States.
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Further Information

Bioactivity:
Atorvastatin is an orally active inhibitor of HMG-CoA reductase,is a lipid-lowering agent (human SV-SMC proliferation and invasion with IC50s of 0.39 μM and 2.39 μM, respectively)
CAS:
134523-00-5
Formula:
C33H35FN2O5
Molecular Weight:
558.65
Pathway:
Autophagy; Metabolism
Purity:
0.9969
SMILES:
CC(C)c1c(C(=O)Nc2ccccc2)c(c(-c2ccc(F)cc2)n1CC[C@@H](O)C[C@@H](O)CC(O)=O)-c1ccccc1
Target:
HMG-CoA Reductase; Autophagy

References

1. Song XJ, et al. Atorvastatin inhibits myocardial cell apoptosis in a rat model with post-myocardial infarction heart failure by downregulating ER stress response. Int J Med Sci. 2011;8(7):564-72. 2. Li Y, et al. Inhibition of endoplasmic reticulum stress signaling pathway: A new mechanism of statins to suppress the development of abdominal aortic aneurysm. PLoS One. 2017 Apr 3;12(4):e0174821. 3. Rongcai Jiang , Shiguang Zhao, Renzhi Wang ,et al. Safety and Efficacy of Atorvastatin for Chronic Subdural Hematoma in Chinese Patients: A Randomized ClinicalTrial.[J]. Jama Neurology, 2018.