TargetMol

Almotriptan

Product Code:
 
TAR-T21231
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T21231-10mg10mg£111.00
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Quantity:
TAR-T21231-1mL1 mL * 10 mM (in DMSO)£122.00
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Quantity:
TAR-T21231-25mg25mg£168.00
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Quantity:
TAR-T21231-50mg50mg£226.00
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Quantity:
TAR-T21231-100mg100mg£310.00
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Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
Almotriptan is a 5-HT1B/1D-receptor agonist used to treat migraine.Almotriptan is a triptan drug for treatment of migraine headaches.Binding of the drug to the receptor leads to vasoconstriction of the cranial blood vessels and thus affects the redistribution of cranial blood flow. Almotriptan significantly increases cerebral blood flow and reduces blood flow through extracerebral cranial vessels.
CAS:
154323-57-6
Formula:
C17H25N3O2S
Molecular Weight:
335.47
Pathway:
Neuroscience; GPCR/G Protein
Purity:
1
SMILES:
CN(C)CCc1c[nH]c2ccc(CS(=O)(=O)N3CCCC3)cc12
Target:
5-HT Receptor

References

1. Abbas Z, Marihal S. Gellan gum-based mucoadhesive microspheres of almotriptan for nasal administration: Formulation optimization using factorial design, characterization, and in vitro evaluation. J Pharm Bioallied Sci. 2014 Oct;6(4):267-77. doi: 10.4103/0975-7406.142959. PubMed PMID: 25400410; PubMed Central PMCID: PMC4231387. 2. Orlandini S, Pasquini B, Stocchero M, Pinzauti S, Furlanetto S. An integrated quality by design and mixture-process variable approach in the development of a capillary electrophoresis method for the analysis of almotriptan and its impurities. J Chromatogr A. 2014 Apr 25;1339:200-9. doi: 10.1016/j.chroma.2014.02.088. Epub 2014 Mar 12. PubMed PMID: 24656544. 3. Castagno E, Lupica M, Viola S, Savino F, Miniero R. Creatin-kinase elevation after accidental ingestion of almotriptan in an 18-month-old girl. Minerva Pediatr. 2014 Feb;66(1):95-7. PubMed PMID: 24608586.