TargetMol

Ibudilast

Product Code:
 
TAR-T2137
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T2137-10mg10mg£102.00
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TAR-T2137-1mL1 mL * 10 mM (in DMSO)£107.00
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TAR-T2137-25mg25mg£109.00
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TAR-T2137-50mg50mg£112.00
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TAR-T2137-100mg100mg£133.00
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TAR-T2137-200mg200mg£152.00
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Further Information

Bioactivity:
Ibudilast(KC-404;AV-411;MN-166) is a relatively nonselective phosphodiesterase inhibitor. It is approved for use as an anti-inflammatory in Japan.
CAS:
50847-11-5
Formula:
C14H18N2O
Molecular Weight:
230.311
Pathway:
Metabolism
Purity:
0.999
SMILES:
CC(C)C(=O)c1c(nn2ccccc12)C(C)C
Target:
PDE

References

1. Yamazaki T, et al. Eur J Pharmacol. 2010 Oct 29. 2. Chen Y, Wang H, Ying Z, et al. Ibudilast enhances the clearance of SOD1 and TDP-43 aggregates through TFEB-mediated autophagy and lysosomal biogenesis: The new molecular mechanism of ibudilast and its implication for neuroprotective therapy[J]. Biochemical and Biophysical Research Communications. 2020.