TargetMol

alpha-Conotoxin imi

Product Code:
 
TAR-T23707
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T23707-10mg10mg£1,061.00
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Further Information

Bioactivity:
alpha-Conotoxin imi is a nicotinic acetylcholine receptor ligand.
CAS:
156467-85-5
Formula:
C52H82N20O15S4
Molecular Weight:
1355.59
Purity:
0.98
SMILES:
C[C@H](NC(=O)[C@H](CS)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@H](CS)NC(=O)[C@H](CS)NC(=O)CN)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CS)C(N)=O

References

1. Mei D, Zhao L, Chen B, Zhang X, Wang X, Yu Z, Ni X, Zhang Q. ?-Conotoxin ImI-modified polymeric micelles as potential nanocarriers for targeted docetaxel delivery to ?7-nAChR overexpressed non-small cell lung cancer. Drug Deliv. 2018 Nov;25(1):493-503. doi: 10.1080/10717544.2018.1436097. PubMed PMID: 29426250. 2. Padilla A, Keating P, Hartmann JX, Mar? F. Effects of ?-conotoxin ImI on TNF-?, IL-8 and TGF-? expression by human macrophage-like cells derived from THP-1 pre-monocytic leukemic cells. Sci Rep. 2017 Oct 6;7(1):12742. doi: 10.1038/s41598-017-11586-2. PubMed PMID: 28986583; PubMed Central PMCID: PMC5630575. 3. Gao B, Peng C, Lin B, Chen Q, Zhang J, Shi Q. Screening and Validation of Highly-Efficient Insecticidal Conotoxins from a Transcriptome-Based Dataset of Chinese Tubular Cone Snail. Toxins (Basel). 2017 Jul 6;9(7). pii: E214. doi: 10.3390/toxins9070214. PubMed PMID: 28684723; PubMed Central PMCID: PMC5535161. 4. Taguchi A, Kobayashi K, Kotani A, Muguruma K, Kobayashi M, Fukumoto K, Takayama K, Hakamata H, Hayashi Y. 3-Nitro-2-pyridinesulfenates as Efficient Solution- and Solid-Phase Disulfide Bond Forming Agents. Chemistry. 2017 Jun 16;23(34):8262-8267. doi: 10.1002/chem.201700952. Epub 2017 May 29. PubMed PMID: 28407456.