TargetMol

Efavirenz

Product Code:
 
TAR-T2393
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T2393-1mL1 mL * 10 mM (in DMSO)£107.00
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TAR-T2393-10mg10mg£109.00
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TAR-T2393-25mg25mg£127.00
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TAR-T2393-50mg50mg£136.00
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Further Information

Bioactivity:
Efavirenz is a Human Immunodeficiency Virus 1 Non-Nucleoside Analog Reverse Transcriptase Inhibitor. The mechanism of action of efavirenz is as a Non-Nucleoside Reverse Transcriptase Inhibitor, and Cytochrome P450 3A Inducer, and Cytochrome P450 2B6 Inducer, and Cytochrome P450 2C9 Inhibitor, and Cytochrome P450 2C19 Inhibitor, and Cytochrome P450 3A4 Inhibitor. The chemical classification of efavirenz is Non-Nucleoside Analog.
CAS:
154598-52-4
Formula:
C14H9ClF3NO2
Molecular Weight:
315.68
Pathway:
Autophagy; Microbiology/Virology; Proteases/Proteasome
Purity:
0.9983
SMILES:
C1CC1C#C[C@]1(c2c(ccc(c2)Cl)NC(=O)O1)C(F)(F)F
Target:
HIV Protease; Reverse Transcriptase; Autophagy

References

1. Braz VA, et al. Biochemistry. 2010, 49(3):601-10. 2. Funes HA, et al. J Antimicrob Chemother. 2015, 70(8):2249-54. 3. Apostolova N, et al. J Hepatol. 2013, 59(4):780-9. 4. Caulk AW, et al. J Biomech. 2015, 48(10):2176-80. 5. Chu, Liuxi, et al. Simultaneous quantitation of zidovudine, efavirenz, lopinavir and ritonavir in human hair by liquid chromatography-atmospheric pressure chemical ionization-tandem mass spectrometry [J]. Journal of Chromatography B . 2018 Oct 15;1097-1098:54-63. 6. Zhang R, Zhang F, Sun Z, et al. LINE-1 Retrotransposition Promotes the Development and Progression of Lung Squamous Cell Carcinoma by Disrupting the Tumor Suppressor Gene FGGY[J]. Cancer research. 2019: canres. 0076.2019.