TargetMol

TAS-117

Product Code:
 
TAR-T28923
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T28923-5mg5mg£1,492.00
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TAR-T28923-50mg50mg£2,946.00
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Quantity:
TAR-T28923-100mg100mg£4,006.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
TAS-117, a PKB/Akt inhibitor, is used potentially for the treatment of solid tumors.
CAS:
1402602-94-1
Formula:
C26H24N4O2
Molecular Weight:
424.504
Purity:
0.98
SMILES:
C[C@@]1(O)C[C@@](N)(C1)c1ccc(cc1)-c1nc2-c3cnccc3OCn2c1-c1ccccc1

References

1. Mimura N, Hideshima T, Shimomura T, Suzuki R, Ohguchi H, Rizq O, Kikuchi S, Yoshida Y, Cottini F, Jakubikova J, Cirstea D, Gorgun G, Minami J, Tai YT, Richardson PG, Utsugi T, Iwama A, Anderson KC. Selective and potent Akt inhibition triggers anti-myeloma activities and enhances fatal endoplasmic reticulum stress induced by proteasome inhibition. Cancer Res. 2014 Aug 15;74(16):4458-69. doi: 10.1158/0008-5472.CAN-13-3652. PubMed PMID: 24934808; PubMed Central PMCID: PMC4140659. 2. Utsugi T. New challenges and inspired answers for anticancer drug discovery and development. Jpn J Clin Oncol. 2013 Oct;43(10):945-53. doi: 10.1093/jjco/hyt131. PubMed PMID: 24014883; PubMed Central PMCID: PMC3787805.