TargetMol

Carisbamate

Product Code:
 
TAR-T30748
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T30748-50mg50mg£1,026.00
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TAR-T30748-100mg100mg£1,669.00
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This product comes from: United States.
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  • Further Information
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Further Information

Bioactivity:
CarisbAMate (JNJ-10234094, RWJ 333369, YKP-509) is an antiepileptic drug candidate.
CAS:
194085-75-1
Formula:
C9H10ClNO3
Molecular Weight:
215.63
Purity:
0.98
SMILES:
NC(=O)OC[C@@H](O)c1ccccc1Cl

References

1. Mangubat EZ, Kellogg RG, Harris TJ Jr, Rossi MA. On-demand pulsatile intracerebral delivery of carisbamate with closed-loop direct neurostimulation therapy in an electrically induced self-sustained focal-onset epilepsy rat model. J Neurosurg. 2015 Jun;122(6):1283-92. doi: 10.3171/2015.1.JNS14946. Epub 2015 Feb 27. PubMed PMID: 25723302. 2. Hadera MG, Faure JB, Berggaard N, Tefera TW, Nehlig A, Sonnewald U. The anticonvulsant actions of carisbamate associate with alterations in astrocyte glutamine metabolism in the lithium-pilocarpine epilepsy model. J Neurochem. 2014 Oct 26;132(5):532-545. doi: 10.1111/jnc.12977. [Epub ahead of print] PubMed PMID: 25345404. 3. Shim S, El Mansari M, Blier P. Modulation of the antidepressant-like effects of sustained administration of carisbamate and lamotrigine on monoaminergic systems: electrophysiological studies in the rat brain. J Pharmacol Exp Ther. 2013 Nov;347(2):487-96. doi: 10.1124/jpet.113.203315. Epub 2013 Aug 28. PubMed PMID: 23986541. 4. Smith T, DiBernardo A, Shi Y, Todd MJ, Brashear HR, Ford LM. Efficacy and safety of carisbamate in patients with diabetic neuropathy or postherpetic neuralgia: results from 3 randomized, double-blind placebo-controlled trials. Pain Pract. 2014 Apr;14(4):332-42. doi: 10.1111/papr.12080. Epub 2013 May 22. PubMed PMID: 23692321.