TargetMol

Aldumastat

Product Code:
 
TAR-T35859
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T35859-5mg5mg£404.00
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TAR-T35859-50mg50mg£1,821.00
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Quantity:
TAR-T35859-100mg100mg£2,319.00
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This product comes from: United States.
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Further Information

Bioactivity:
Aldumastat (GLPG1972; S201086) is a potent, seletive and orally active ADAMTS-5 (IC50=19 nM) inhibitor, and has 8-fold seletivity over ADAMTS-4 (IC50=156 nM). Aldumastat has anticatabolic activity and is used for osteoarthritis research[1].
CAS:
1957278-93-1
Formula:
C20H24F2N4O3
Molecular Weight:
406.43
Purity:
0.98
SMILES:
N/A

References

Franck Brebion, et al. Discovery of GLPG1972/S201086, a Potent, Selective, and Orally Bioavailable ADAMTS-5 Inhibitor for the Treatment of Osteoarthritis. J Med Chem. 2021 Mar 25;64(6):2937-2952.