TargetMol

S65487

Product Code:
 
TAR-T36897
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T36897-10mg10mg£631.00
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TAR-T36897-25mg25mg£1,267.00
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TAR-T36897-50mg50mg£2,062.00
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Quantity:
TAR-T36897-100mg100mg£3,131.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
S65487 (VOB560) is a potent and selective Bcl-2 inhibitor. S65487 is also active on BCL-2 mutations, such as G101V and D103Y. S65487 has poor affinity with MCL-1, BFL-1 and BCL-XL. S65487 induces apoptosis and has anticaner activities[1][2].
CAS:
1644600-79-2
Formula:
C41H41ClN6O4
Molecular Weight:
717.26
Purity:
0.98
SMILES:
N/A

References

Arnaud Le Tiran, et al. Abstract 1276: Identification of S65487/VOB560 as a potent and selective intravenous 2nd-generation BCL-2 inhibitor active in wild-type and clinical mutants resistant to Venetoclax. Cancer Research. July 2021. American Association for Cancer Research, AACR. 2021.4.10-15.