TargetMol

5 α-Androst-16-en-3 α-ol

Product Code:
 
TAR-T37194
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T37194-10mg10mg£124.00
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TAR-T37194-50mg50mg£294.00
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TAR-T37194-100mg100mg£406.00
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Further Information

Bioactivity:
5α-Androst-16-en-3α-ol is a steroid pheromone that has been found in boar testes and human male axillary sweat and has diverse biological activities.1,2It enhances GABA-activated currents in primary mouse cerebellar granule cells (EC50= 0.4 μM).25α-Androst-16-en-3α-ol (0.1-1 μM) increases the amplitude of GABA-activated currents in HEK293 cells expressing human α1β2γ2and α2β2γ2subunit-containing GABAAreceptors.
CAS:
1153-51-1
Formula:
C19H30O
Molecular Weight:
274.4
Purity:
0.98
SMILES:
C[C@@]12[C@]3([H])[C@](CC[C@@]1([H])C[C@@H](CC2)O)([H])[C@@]4([H])[C@](CC3)(C=CC4)C

References

Kaminski, R.M., Marini, H., Ortinski, P.I., et al.The pheromone androstenol (5?-androst-16-en-3?-ol) is a neurosteroid positive modulator of GABAA receptorsJ. Pharmacol. Exp. Ther.317(2)694-703(2006) Brooksbank, B.W., Brown, R., and Gustafsson, J.A.The detection of 5?-androst-16-en-3?-ol in human male axillary sweatExperientia30(8)864-865(1974)