TargetMol

3-Hydroxykynurenine

Product Code:
 
TAR-T37683
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T37683-5mg5mg£189.00
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Quantity:
TAR-T37683-10mg10mg£254.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
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This product comes from: United States.
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Further Information

Bioactivity:
3-Hydroxykynurenine is an active metabolite of tryptophan and inhibits yeast and rat liver aldehyde dehydrogenase by 97 and 69%.
CAS:
484-78-6
Formula:
C10H12N2O4
Molecular Weight:
224.21
Purity:
0.9969
SMILES:
O=C(O)C(N)CC(=O)C=1C=CC=C(O)C1N

References

Badawy, A.A.-B., and Morgan, C.J. Tryptophan metabolites as potent inhibitors of aldehyde dehydrogenase activity and potential alcoholism-aversion therapeutic agents. Int. Congr. Ser. 1304, 344-351 (2007). S Okuda, et al. 3-Hydroxykynurenine, an endogenous oxidative stress generator, causes neuronal cell death with apoptotic features and region selectivity. J Neurochem. 1998 Jan;70(1):299-307. Sarah S Zaher,et al. 3-hydroxykynurenine suppresses CD4+ T-cell proliferation, induces T-regulatory-cell development, and prolongs corneal allograft survival. Invest Ophthalmol Vis Sci. 2011 Apr 22;52(5):2640-8.