TargetMol

gamma-Linolenic acid

Product Code:
 
TAR-T4868
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T4868-10mg10mg£102.00
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Quantity:
TAR-T4868-1mL1 mL * 10 mM (in DMSO)£111.00
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TAR-T4868-25mg25mg£122.00
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TAR-T4868-50mg50mg£148.00
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Quantity:
TAR-T4868-100mg100mg£185.00
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Quantity:
TAR-T4868-200mg200mg£241.00
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Quantity:
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This product comes from: United States.
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Further Information

Bioactivity:
γ-Linolenic acid, is an unsaturated fatty acid synthesized from linoleic acid (LA) by the enzyme delta-6-desaturase. Research on hepatocellular cell lines has shown γ-Linolenic Acid to have induced reactive oxygen species generation including lipid peroxidation, cell growth inhibition, and heme oxygenase-1 production for antioxidant protection against oxidative stress. Further experiments have noted that γ-Linolenic acid inhibits inflammatory responses through inactivation of NFκB and activator protein-1 by suppressed oxidative stress.
CAS:
506-26-3
Formula:
C18H30O2
Molecular Weight:
278.436
Pathway:
Metabolism
Purity:
0.9921
SMILES:
CCCCCC=C/CC=C/CC=C/CCCCC(O)=O
Target:
Endogenous Metabolite

References

Dercksen M , Kulik W , Mienie L J , et al. Polyunsaturated fatty acid status in treated isovaleric acidemia patients[J]. European Journal of Clinical Nutrition, 2016, 70(10). Sinha R , Ahn J , Sampson J N , et al. Fecal Microbiota, Fecal Metabolome, and Colorectal Cancer Interrelations[J]. PLOS ONE, 2016, 11(3):e0152126. Ziboh V A , Miller C C , Cho Y . Metabolism of polyunsaturated fatty acids by skin epidermal enzymes: generation of antiinflammatory and antiproliferative metabolites[J]. American Journal of Clinical Nutrition, 2000, 71(1 Suppl):361S. Kankaanp?? P E , Salminen S J , Isolauri E , et al. The influence of polyunsaturated fatty acids on probiotic growth and adhesion. FEMS Microbiology Letters, 2001, 194(2):149-153.