TargetMol

DL-Glyceraldehyde

Product Code:
 
TAR-T4918
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T4918-1mL1 mL * 10 mM (in DMSO)£107.00
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TAR-T4918-10mg10mg£109.00
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TAR-T4918-25mg25mg£132.00
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TAR-T4918-50mg50mg£162.00
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TAR-T4918-100mg100mg£208.00
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TAR-T4918-200mg200mg£277.00
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TAR-T4918-500mg500mg£428.00
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Further Information

Bioactivity:
Glyceraldehyde is produced from the action of the enzyme glyceraldehyde dehydrogenase, which converts glycerol to glyceraldehyde using NADP as a cofactor. When present at sufficiently high levels, glyceraldehyde can be a cytotoxin and a mutagen. A cytotoxin is a compound that kills cells. A mutagen is a compound that causes mutations in DNA. Glyceraldehyde is a highly reactive compound that can modify and cross-link proteins. Glyceraldehyde-modified proteins appear to be cytotoxic, depress intracellular glutathione levels, and induce reactive oxygen species (ROS) production (PMID: 14981296 ). Glyceraldehyde has been shown to cause chromosome damage to human cells in culture and is mutagenic in the Ames bacterial test.
CAS:
56-82-6
Formula:
C3H6O3
Molecular Weight:
90.078
Pathway:
Endocrinology/Hormones; Metabolism
Purity:
0.9588
SMILES:
OCC(O)C=O
Target:
Reductase

References

Gugliucci A . A practical method to study functional impairment of proteins by glycation and effects of inhibitors using current coagulation/fibrinolysis reagent kits[J]. Clinical Biochemistry, 2003, 36(2):155-158. Beard K M , Shangari N , Wu B , et al. Metabolism, not autoxidation, plays a role in alpha-oxoaldehyde- and reducing sugar-induced erythrocyte GSH depletion: relevance for diabetes mellitus.[J]. Molecular & Cellular Biochemistry, 2003, 252(1-2):331-338.