TargetMol

Gamabufotalin

Product Code:
 
TAR-T4A2456
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T4A2456-1mg1mg£168.00
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Quantity:
TAR-T4A2456-1mL1 mL * 10 mM (in DMSO)£173.00
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TAR-T4A2456-5mg5mg£309.00
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TAR-T4A2456-10mg10mg£425.00
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Quantity:
TAR-T4A2456-25mg25mg£656.00
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TAR-T4A2456-50mg50mg£863.00
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Further Information

Bioactivity:
1. Gamabufotalin , a major bufadienolide of Chansu, has been used for treatment of COX-2-mediated diseases and cancer therapy due to its desirable metabolic stability and less adverse effect.
CAS:
465-11-2
Formula:
C24H34O5
Molecular Weight:
402.531
Pathway:
Neuroscience; Immunology/Inflammation
Purity:
0.9924
SMILES:
C[C@]12C[C@@H](O)[C@H]3[C@@H](CC[C@@H]4C[C@@H](O)CC[C@]34C)[C@@]1(O)CC[C@@H]2c1ccc(=O)oc1
Target:
COX

References

Yu Z , Guo W , Ma X , et al. Gamabufotalin, a bufadienolide compound from toad venom, suppresses COX-2 expression through targeting IKK?/NF-?B signaling pathway in lung cancer cells[J]. Molecular Cancer, 2014, 13(1):203.