TargetMol

Terutroban

Product Code:
 
TAR-T5505
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T5505-5mg5mg£107.00
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Quantity:
TAR-T5505-1mL1 mL * 10 mM (in DMSO)£115.00
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Quantity:
TAR-T5505-10mg10mg£128.00
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This product comes from: United States.
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Further Information

Bioactivity:
Terutroban, a thromboxane prostaglandin receptor antagonist, affects the progression of atherosclerosis.
CAS:
165538-40-9
Formula:
C20H22ClNO4S
Molecular Weight:
407.91
Pathway:
GPCR/G Protein; Immunology/Inflammation
Purity:
0.98
SMILES:
Cc1ccc2C[C@@H](CCc2c1CCC(O)=O)NS(=O)(=O)c1ccc(Cl)cc1
Target:
Prostaglandin Receptor

References

Lesault PF, et al. Daily administration of the TP receptor antagonist terutroban improved endothelial function in high-cardiovascular-risk patients with atherosclerosis. Br J Clin Pharmacol.2011 Jun;71(6):844-851. Bots ML, et al. Thromboxane prostaglandin receptor antagonist and carotid atherosclerosis progression in patients with cerebrovascular disease of ischemic origin: a randomized controlled trial. Stroke. 2014 Aug;45(8):2348-2353. De La Cruz JP, et al. Effects of terutroban, a thromboxane/prostaglandin endoperoxide receptor antagonist, on retinal vascularity in diabetic rats. Diabetes Metab Res Rev. 2012 Feb;28(2):132-138.