TargetMol

Trametinib (DMSO solvate)

Product Code:
 
TAR-T5857
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T5857-10mg10mg£103.00
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Quantity:
TAR-T5857-1mL1 mL * 10 mM (in DMSO)£111.00
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Quantity:
TAR-T5857-25mg25mg£114.00
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Quantity:
TAR-T5857-50mg50mg£116.00
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Quantity:
TAR-T5857-100mg100mg£136.00
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Quantity:
TAR-T5857-200mg200mg£164.00
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Quantity:
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This product comes from: United States.
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Further Information

Bioactivity:
Trametinib DMSO solvate is a Highly Potent and Selective MEK Inhibitor that specifically inhibits MEK1/2(IC50 :2 nM)
CAS:
1187431-43-1
Formula:
C28H29FIN5O5S
Molecular Weight:
693.53
Pathway:
Apoptosis; MAPK
Purity:
0.9971
SMILES:
CS(C)=O.CC(=O)Nc1cccc(c1)-n1c2c(C)c(=O)n(C)c(Nc3ccc(I)cc3F)c2c(=O)n(C2CC2)c1=O
Target:
Apoptosis; MEK

References

Abe H , Kikuchi S , Hayakawa K , et al. Discovery of a Highly Potent and Selective MEK Inhibitor: GSK1120212 (JTP-74057 DMSO Solvate)[J]. ACS MEDICINAL CHEMISTRY LETTERS, 2011, 2(4):320-324.